When John Manley tested positive for COVID-19, his sister urged him to get on the malaria drug that she’d heard Fox News hosts plugging and that President Donald Trump was heralding as a potential “game changer” for fighting the coronavirus. “It caused a huge rift in the family because the science wasn’t behind it,” said Manley, who lives in Stuttgart, Germany, and whose wife, Heidi Mathis, also tested positive for the virus after a visit to New York. Both have since recovered, and the FDA has advised people not to take the drug outside a hospital or clinical trial.